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    Dear all,<br>
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      <font size="+1" face="Calibri">Please find below two open
        positions available at the INS, in Marseille, France. </font><font
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            <h1 class="main_title" style="margin: -10px 0px 0px;
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              text-decoration-style: initial; text-decoration-color:
              initial;">Post-doctoral position in the Theoretical
              Neuroscience Group - INS, Marseille, France<br>
            </h1>
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                    background: transparent;">Summary</b></span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  baseline; background: transparent;">The Theoretical
                  Neuroscience Group (Head: Viktor Jirsa) is seeking to
                  fill a post-doctoral position in the context of the
                  project EPINOV to work on statistical & dynamical
                  modeling of seizure propagation using personalized
                  brain modeling and neuroinformatics approaches on a
                  cohort of hundreds of epilepsy patients. EPINOV is one
                  of 10 large-scale projects selected in the 3rd round
                  of French scientific excellence program «RHU» managed
                  by the National Research Agency (ANR). The aim of the
                  EPINOV project is to significantly improve presurgical
                  interpretation, guide surgical strategies and
                  translate computational tools into clinical routine of
                  personalized medicine. We use individual MRI scans to
                  reconstruct brain anatomy and connectivity, which are
                  combined with a neural mass model and fit using the
                  Bayesian modeling software Stan to individuals’
                  intracranial electrophysiology data (stereotactic
                  EEG), validated by clinical data from other
                  modalities, such as MEG, fMRI, and semiology.</span></font></p>
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                    background: transparent;">Responsibilities</b></span></font></p>
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                  baseline; background: transparent;">• Scale up
                  statistical models “vertically” to handle more data
                  and higher resolution anatomy, using model comparison
                  techniques to evaluate the advantage of different
                  model structures</span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  style="margin: 0px; padding: 0px; border: 0px;
                  outline: 0px; font-size: medium; vertical-align:
                  baseline; background: transparent;">• Scale out models
                  “horizontally”, performing coherent, reliable
                  inference across a large cohort of patients using
                  dedicated, on-site HPC resources</span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  style="margin: 0px; padding: 0px; border: 0px;
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                  baseline; background: transparent;">• Develop routines
                  to evaluate and visualize inference results, making
                  them amenable to clinical interpretation</span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  baseline; background: transparent;">• Integrate
                  developed code into existing code bases and pipelines</span></font></p>
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                    background: transparent;">Qualification</b><b
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            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  baseline; background: transparent;">• Highly motivated
                  to work on an interdisciplinary project and
                  collaborate with the various members of the
                  consortium. </span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  baseline; background: transparent;">• PhD degree in
                  computational neuroscience, mathematical or
                  statistical modeling, machine learning or equivalent
                  level of knowledge. </span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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              letter-spacing: normal; text-align: left; text-indent:
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              text-decoration-color: initial;"><font face="Calibri"><span
                  style="margin: 0px; padding: 0px; border: 0px;
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                  baseline; background: transparent;">• Significant,
                  demonstrable experience in data fitting (Bayesian
                  modeling, Dynamical Causal Modeling (DCM), Monte
                  Carlo, etc) will be highly appreciated. </span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  baseline; background: transparent;">• Experience with
                  working in a Linux/HPC environment</span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  baseline; background: transparent;">• Programming in a
                  numerically oriented language (R, Python, MATLAB) </span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  outline: 0px; font-size: medium; vertical-align:
                  baseline; background: transparent;">• Familiarity with
                  Git, unit testing, Docker/VMs is a plus</span></font></p>
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                    font-size: 16px; vertical-align: baseline;
                    background: transparent;">The Theoretical
                    Neuroscience group</b><b style="margin: 0px;
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                    16px; vertical-align: baseline; background:
                    transparent;"> </b></span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
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                  baseline; background: transparent;">We are a
                  multi-national team interested in understanding the
                  mechanisms underlying the spatiotemporal organization
                  of large-scale brain networks. Our work comprises
                  mathematical and computational modeling of large-scale
                  network dynamics and human brain imaging data, the
                  development of neuroinformatics tools for studying
                  large-scale brain networks applied to concrete
                  functions, dysfunctions (epilepsy, dementia) and
                  aging.</span></font></p>
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                    0px; padding: 0px; border: 0px; outline: 0px;
                    font-size: 16px; vertical-align: baseline;
                    background: transparent;">Terms of salary and
                    employment</b><b style="margin: 0px; padding: 0px;
                    border: 0px; outline: 0px; font-size: 16px;
                    vertical-align: baseline; background: transparent;"> </b></span></font></p>
            <p style="margin: 0px; padding: 0px; border: 0px none;
              outline: 0px none; font-size: 13px; vertical-align:
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              font-variant-caps: normal; font-weight: normal;
              letter-spacing: normal; text-align: left; text-indent:
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                  style="margin: 0px; padding: 0px; border: 0px;
                  outline: 0px; font-size: medium; vertical-align:
                  baseline; background: transparent;">A 12-month
                  renewable contract will be established. Salary will
                  depend on the diploma and experience. Operating
                  language in the laboratory is English. Applications
                  including a cover letter, curriculum vitae and the
                  names of two referees should be sent by September 30th
                  2017 to: Dr. Irene Yujnovsky at <a
                    moz-do-not-send="true" class="mailto-link"
                    href="mailto:irene.yujnovsky@univ-amu.fr"
                    target="_blank" rel="noopener noreferrer"
                    style="margin: 0px; padding: 0px; border: 0px none;
                    outline: 0px none; font-size: 16px; vertical-align:
                    baseline; background: transparent none repeat scroll
                    0% 0%; text-decoration: none;">irene.yujnovsky@univ-amu.fr</a> </span></font></p>
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                  style="margin: 0px; padding: 0px; border: 0px;
                  outline: 0px; font-size: medium; vertical-align:
                  baseline; background: transparent;">More information
                  about the INS and the Theoretical Neurosciences Group
                  can be found at: <a moz-do-not-send="true"
                    href="http://ins.univ-amu.fr/" target="_blank"
                    rel="noopener noreferrer" style="margin: 0px;
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                  </a></span></font></p>
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                    href="http://ins.univ-amu.fr/" target="_blank"
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                  </a></span></font></p>
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              outline: 0px none; font-size: 13px; vertical-align:
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              letter-spacing: normal; text-align: left; text-indent:
              0px; text-transform: none; white-space: normal;
              word-spacing: 0px; text-decoration-style: initial;
              text-decoration-color: initial;"><a moz-do-not-send="true"
                href="http://ins.univ-amu.fr/" target="_blank"
                rel="noopener noreferrer" style="margin: 0px; padding:
                0px; border: 0px none; outline: 0px none; font-size:
                16px; vertical-align: baseline; background: transparent
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              </a><b><span
style="font-size:13.0pt;font-family:"Verdana",sans-serif;mso-bidi-font-family:Arial;mso-ansi-language:FR"
                  lang="FR">Clinical data manager for national
                  consortium on epilepsy surgery - </span></b><b><span
                  style="font-size:13.0pt;
font-family:"Verdana",sans-serif;mso-ansi-language:FR"
                  lang="FR">Aix-Marseille Université <o:p></o:p></span></b>
            </p>
            <p class="MsoNormal" style="tab-stops:0in"><b><span
                  style="font-size:
13.0pt;font-family:"Verdana",sans-serif;mso-ansi-language:FR"
                  lang="FR">Marseille, FRANCE<o:p></o:p></span></b></p>
            <p class="MsoNormal" style="tab-stops:0in"><b><span
                  style="font-size:
13.0pt;font-family:"Verdana",sans-serif;mso-bidi-font-family:Arial;mso-ansi-language:
                  FR" lang="FR"><o:p> </o:p></span></b></p>
            <p class="MsoNormal"><b><span
                  style="font-family:"Verdana",sans-serif;
                  mso-ansi-language:FR" lang="FR"><o:p> </o:p></span></b></p>
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-size:11.0pt;
font-family:"Verdana",sans-serif;mso-bidi-font-weight:bold">A
                position for an experienced clinical data manager is
                open to create and maintain an epileptic patient
                database including registration, normalization and
                security issues and to ensure the communication with the
                key partners in the academic, clinical and industry
                sectors with the aim </span><span
                style="font-size:11.0pt;font-family:
                "Verdana",sans-serif">of generating individual
                Virtual Patient models using The Virtual Brain (TVB)
                platform as framework (see <a moz-do-not-send="true"
                  class="moz-txt-link-freetext"
                  href="http://www.thevirtualbrain.org">http://www.thevirtualbrain.org</a>).<i
                  style="mso-bidi-font-style:normal"> </i>This database
                will be generated in the context of the EPINOV (<i
                  style="mso-bidi-font-style:normal">Improving EPilepsy
                  surgery management and progNOsis using Virtual brain
                  technology) </i>project<span
                  style="mso-bidi-font-weight:bold"> led by Professor
                  Fabrice Bartolomei (</span></span><a
                moz-do-not-send="true"
href="http://fr.ap-hm.fr/service/neurophysiologie-clinique-hopital-timone"><span
style="font-size:11.0pt;font-family:"Verdana",sans-serif">http://fr.ap-hm.fr/service/neurophysiologie-clinique-hopital-timone</span></a><span
style="font-size:11.0pt;font-family:"Verdana",sans-serif;mso-bidi-font-weight:
                bold">) funded by the RHU programme.<o:p></o:p></span></p>
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-size:11.0pt;
font-family:"Verdana",sans-serif;mso-bidi-font-weight:bold"><o:p> </o:p></span></p>
            <p class="MsoNormal" style="text-align:justify"><b><span
                  style="font-size:11.0pt;
                  font-family:"Verdana",sans-serif">Qualification<o:p></o:p></span></b></p>
            <p class="MsoNormal" style="text-align:justify"><b><span
                  style="font-size:11.0pt;
                  font-family:"Verdana",sans-serif"><o:p> </o:p></span></b></p>
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-size:11.0pt;
font-family:"Verdana",sans-serif;mso-bidi-font-weight:bold">Candidates
                must be highly motivated to work on an interdisciplinary
                project and collaborate with the various members of the
                consortium. They should have a degree in biomedical
                engineering, medical informatics or equivalent level of
                knowledge. Candidates must possess a solid experience in
                management of clinical and/or research data and
                programming (C, MATLAB, Python). Experience with
                neuroimaging data (stereotactic EEG, MRI, DTI, MEG,
                EEG), clinical trials, neuroinformatics and its standard
                formats (for instance DICOM, XNAT, BIDS), machine
                learning and Big Data would be considered an advantage.
                <o:p></o:p></span></p>
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-size:11.0pt;
font-family:"Verdana",sans-serif;mso-bidi-font-weight:bold"><o:p> </o:p></span></p>
            <p class="MsoNormal" style="text-align:justify"><b
                style="mso-bidi-font-weight: normal"><span
                  style="font-size:11.0pt;font-family:"Verdana",sans-serif;
                  mso-bidi-font-family:Arial">The EPINOV project and
                  consortium <o:p></o:p></span></b></p>
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-size:11.0pt;
font-family:"Verdana",sans-serif;mso-bidi-font-family:Arial">We
                are a national consortium </span><span
                style="font-size:11.0pt;font-family:"Verdana",sans-serif;
                mso-fareast-font-family:"MS
                Mincho";mso-bidi-font-family:"Trebuchet
                MS"; mso-fareast-language:FR">composed of
                clinicians, researchers and industrial partners
                interested in </span><span
                style="font-size:11.0pt;font-family:"Verdana",sans-serif">improving
                epilepsy surgical prognosis using large–scale brain
                modelling based on individual epileptic patient data. A
                prospective, randomized multicenter trial will be
                conducted with subjects suffering from drug-resistant
                epilepsy. The clinical trial will systematically
                evaluate the added value of personalized brain modelling
                in the surgical decision making. <o:p></o:p></span></p>
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-size:11.0pt;
                font-family:"Verdana",sans-serif"><o:p> </o:p></span></p>
            <p class="MsoNormal" style="text-align:justify"><b
                style="mso-bidi-font-weight: normal"><span
                  style="font-size:11.0pt;font-family:"Verdana",sans-serif;
                  mso-bidi-font-family:Arial">Terms of salary and
                  employment<o:p></o:p></span></b></p>
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-size:11.0pt;
font-family:"Verdana",sans-serif;mso-bidi-font-family:Arial">Salary
                will depend on the diploma and previous experience. </span><span
                style="font-size:11.0pt;
font-family:"Verdana",sans-serif;mso-bidi-font-weight:bold">Operating
                languages in the consortium are both French and English.
                <o:p></o:p></span></p>
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-size:11.0pt;
font-family:"Verdana",sans-serif;mso-bidi-font-weight:bold"><o:p> </o:p></span></p>
            <pre style="text-align:justify"><span style="font-size:11.0pt;
font-family:"Verdana",sans-serif;mso-bidi-font-weight:bold" lang="EN-GB">Applications including a cover letter, curriculum vitae and the names of two referees should be sent by October 31st 2017 to: <b>Dr. Irene Yujnovsky</b> at </span><span style="font-size:11.0pt;font-family:"Verdana",sans-serif" lang="EN-GB"><a moz-do-not-send="true" class="moz-txt-link-abbreviated" href="mailto:irene.yujnovsky@univ-amu.fr">irene.yujnovsky@univ-amu.fr</a><o:p></o:p></span></pre>
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