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<title>SAVE THE DATE: ICTALS July 4-8 2022 in Bern, Switzerland</title>
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<pre style="text-align: left;"><span style="font-size:12px"><span style="font-family:arial,helvetica neue,helvetica,sans-serif">Dear friends of ICTALS,
We are looking forward to hosting the International Conference on Technology and
AnaLysis of Seizures on the occasion of its 20th anniversary from <strong><span style="color:#1f3864">July 4 to 8 2022 in Bern, Switzerland.</span>
</strong>The 2022 edition of ICTALS, entitled “The tipping point” will inscribe itself into the long tradition of aiming at forecasting seizures.
It will put emphasis on a deeper understanding of possible factors that may help attain this goal.
Please take a look at our <strong><a href="https://insel.us20.list-manage.com/track/click?u=7064a8f391a0fb7cb52c90f2c&id=036cec0a0a&e=d025f4a434" target="_blank" style="mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #007C89;font-weight: normal;text-decoration: underline;"><span style="color:#1f3864">preliminary program</span><span style="color:#1f3864"> </span></a></strong>and get ready for registration early next year.
We would be pleased to welcome you next year in Bern.
Yours sincerely,
<span style="color:#1f3864"><strong>Chairs</strong></span>
Maxime Baud, MD, PhD
Christian Rummel, PhD
<span style="color:#1f3864"><strong>Local organizing committee</strong></span>
Athina Tzovara, PhD
Georgia Ramantani, MD
Antoine Adamantidis, PhD
Kaspar Schindler, MD, PhD
Frédéric Zubler, MD, PhD
Timothée Proix, PhD</span></span>
</pre>
<hr>
<p dir="ltr" style="text-align: left;margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-family: Helvetica;font-size: 16px;line-height: 150%;"><br>
<span style="color:#1f3864"><span style="font-size:12px"><span style="font-family:arial,helvetica neue,helvetica,sans-serif"><strong>Important dates</strong></span></span></span></p>
<p dir="ltr" style="text-align: left;margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-family: Helvetica;font-size: 16px;line-height: 150%;"><span style="font-size:12px"><span style="font-family:arial,helvetica neue,helvetica,sans-serif"><strong>January 17, 2022</strong> registration and abstract submission opens</span><br>
<span style="font-family:arial,helvetica neue,helvetica,sans-serif"><strong>February 28, 2022 </strong></span>early bird registration closes<br>
<span style="font-family:arial,helvetica neue,helvetica,sans-serif"><strong>February 28, 2022 </strong></span>abstract deadline<br>
<span style="font-family:arial,helvetica neue,helvetica,sans-serif"><strong>April 20, 2022</strong> abstract acceptance announcement</span><br>
<span style="font-family:arial,helvetica neue,helvetica,sans-serif"><strong>April 30, 2022</strong> registration closes </span></span></p>
<p dir="ltr" style="text-align: left;margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-family: Helvetica;font-size: 16px;line-height: 150%;"><br>
<span style="font-size:12px"><span style="font-family:arial,helvetica neue,helvetica,sans-serif"><strong><span style="color:#1f3864">Our tradition</span> </strong>- The ICTALS conference attracts scientists and clinicians around one common goal: use quantitative methods to analyze seizures and better understand and treat the disorder. The conference was born in the early 2000s as an International Workshop on Seizure Prediction, when it became clear that ready-to-use statistical solutions for forecasting physical phenomena such as earthquakes would fail at forecasting seizures in the epileptic brain. Since then, a total of nine conferences took place every other year, gathering between 150 and 200 neurologists, physicists, engineers, mathematicians and neuroscientists who all share an interest for quantitative methodology applied to the analysis of neurophysiological signals like EEG. Over the years, the community has increasingly recognized that a deeper understanding of epilepsy was a necessary first step for the engineering of practical solutions for forecasting. Today, the conference is a lively event, with a focus on open-minded debates between experts about hot scientific issues. At ICTALS there is not one single session without a flurry of questions that challenge the schedule. By training the next generation of scientists in epilepsy, ICTALS puts an emphasis on building a community of smart young minds that care about the devastating consequences of the disorder. We strive to harness all modern technology for the better care of people with epilepsy.</span></span></p>
<p dir="ltr" style="text-align: left;margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-family: Helvetica;font-size: 16px;line-height: 150%;"> </p>
<p dir="ltr" style="text-align: left;margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-family: Helvetica;font-size: 16px;line-height: 150%;"><span style="font-size:12px"><span style="font-family:arial,helvetica neue,helvetica,sans-serif"><span style="color:#1f3864"><strong>What’s on the menu in 2022</strong> </span>– After a training day dedicated especially but not exclusively to students and early-career scientists, the four-day conference will follow a logical development starting from “what people with epilepsy tell us” to quantitative objectivation that “what they tell us is measurable”. On the second day, we will move to animal models that reproduce core phenomenological aspects of the disorder, with a special emphasis on the tipping point, i.e. when and how neuronal firing abruptly switches behavior to transition to the ictal state. We will then learn from computational models of this transition, bringing our understanding to a formal theoretical level. We will also debate that any model of the brain, if done correctly, should have the potential to spontaneously develop a seizure. On the third day, we will dive into the pitfalls and prospects of seizure forecasting and ask a very fundamental question just before jumping on a train for our excursion to the lovely Bernese Alps: what does a 50% seizure probability actually mean? For those who find 30 minutes a short time to answer this question, we will have plenty of time during our stroll in the Alps to continue the debate, while looking at breathtaking views. The excursion will finish with traditional Swiss cheese dishes before returning to Bern. On the last day, we will review concrete engineering achievements and tackle challenges that remain to make seizure forecasting possible. </span></span></p>
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