[Neuroinfo] Open positions at INS, Marseille
Irene Yujnovsky
irene.yujnovsky at univ-amu.fr
Tue Sep 26 11:00:11 CEST 2017
Dear all,
Please find below two open positions available at the INS, in Marseille,
France.
Post-doctoral position in the Theoretical Neuroscience Group - INS,
Marseille, France
*Summary*
The Theoretical Neuroscience Group (Head: Viktor Jirsa) is seeking to
fill a post-doctoral position in the context of the project EPINOV to
work on statistical & dynamical modeling of seizure propagation using
personalized brain modeling and neuroinformatics approaches on a cohort
of hundreds of epilepsy patients. EPINOV is one of 10 large-scale
projects selected in the 3rd round of French scientific excellence
program «RHU» managed by the National Research Agency (ANR). The aim of
the EPINOV project is to significantly improve presurgical
interpretation, guide surgical strategies and translate computational
tools into clinical routine of personalized medicine. We use individual
MRI scans to reconstruct brain anatomy and connectivity, which are
combined with a neural mass model and fit using the Bayesian modeling
software Stan to individuals’ intracranial electrophysiology data
(stereotactic EEG), validated by clinical data from other modalities,
such as MEG, fMRI, and semiology.
*Responsibilities*
• Scale up statistical models “vertically” to handle more data and
higher resolution anatomy, using model comparison techniques to evaluate
the advantage of different model structures
• Scale out models “horizontally”, performing coherent, reliable
inference across a large cohort of patients using dedicated, on-site HPC
resources
• Develop routines to evaluate and visualize inference results, making
them amenable to clinical interpretation
• Integrate developed code into existing code bases and pipelines
*Qualification***
• Highly motivated to work on an interdisciplinary project and
collaborate with the various members of the consortium.
• PhD degree in computational neuroscience, mathematical or statistical
modeling, machine learning or equivalent level of knowledge.
• Significant, demonstrable experience in data fitting (Bayesian
modeling, Dynamical Causal Modeling (DCM), Monte Carlo, etc) will be
highly appreciated.
• Experience with working in a Linux/HPC environment
• Programming in a numerically oriented language (R, Python, MATLAB)
• Familiarity with Git, unit testing, Docker/VMs is a plus
*The Theoretical Neuroscience group***
We are a multi-national team interested in understanding the mechanisms
underlying the spatiotemporal organization of large-scale brain
networks. Our work comprises mathematical and computational modeling of
large-scale network dynamics and human brain imaging data, the
development of neuroinformatics tools for studying large-scale brain
networks applied to concrete functions, dysfunctions (epilepsy,
dementia) and aging.
*Terms of salary and employment***
A 12-month renewable contract will be established. Salary will depend on
the diploma and experience. Operating language in the laboratory is
English. Applications including a cover letter, curriculum vitae and the
names of two referees should be sent by September 30th 2017 to: Dr.
Irene Yujnovsky at irene.yujnovsky at univ-amu.fr
<mailto:irene.yujnovsky at univ-amu.fr>
More information about the INS and the Theoretical Neurosciences Group
can be found at: http://ins.univ-amu.fr <http://ins.univ-amu.fr/>
<http://ins.univ-amu.fr/>
<http://ins.univ-amu.fr/>
<http://ins.univ-amu.fr/>*Clinical data manager for national consortium
on epilepsy surgery - **Aix-Marseille Université *
*Marseille, FRANCE*
**
**
A position for an experienced clinical data manager is open to create
and maintain an epileptic patient database including registration,
normalization and security issues and to ensure the communication with
the key partners in the academic, clinical and industry sectors with the
aim of generating individual Virtual Patient models using The Virtual
Brain (TVB) platform as framework (see
http://www.thevirtualbrain.org).//This database will be generated in the
context of the EPINOV (/Improving EPilepsy surgery management and
progNOsis using Virtual brain technology) /projectled by Professor
Fabrice Bartolomei
(http://fr.ap-hm.fr/service/neurophysiologie-clinique-hopital-timone)
funded by the RHU programme.
*Qualification*
**
Candidates must be highly motivated to work on an interdisciplinary
project and collaborate with the various members of the consortium. They
should have a degree in biomedical engineering, medical informatics or
equivalent level of knowledge. Candidates must possess a solid
experience in management of clinical and/or research data and
programming (C, MATLAB, Python). Experience with neuroimaging data
(stereotactic EEG, MRI, DTI, MEG, EEG), clinical trials,
neuroinformatics and its standard formats (for instance DICOM, XNAT,
BIDS), machine learning and Big Data would be considered an advantage.
*The EPINOV project and consortium *
We are a national consortium composed of clinicians, researchers and
industrial partners interested in improving epilepsy surgical prognosis
using large–scale brain modelling based on individual epileptic patient
data. A prospective, randomized multicenter trial will be conducted with
subjects suffering from drug-resistant epilepsy. The clinical trial will
systematically evaluate the added value of personalized brain modelling
in the surgical decision making.
*Terms of salary and employment*
Salary will depend on the diploma and previous experience. Operating
languages in the consortium are both French and English.
Applications including a cover letter, curriculum vitae and the names of
two referees should be sent by October 31st 2017 to: *Dr. Irene
Yujnovsky* at irene.yujnovsky at univ-amu.fr
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